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For 1 hour before and 1 hour immediately after doses eight and 9, the participant’s diet program (oral intake) was restricted to crystal clear liquids only. Contributors in demo B also received 3 consecutive twenty mg each day doses of paroxetine beginning one day right before Just about every procedure section. Paroxetine concentrations have been quantified by sampling blood instantly prior to the ninth dose of review drug in Just about every cure section (Quest Diagnostics, West Valley City, Utah). Blood was gathered to test the CYP2D6 genotype following the ninth dose of study drug of the first phase in trial A and at screening in trial B. The top of the review in each trials consisted of the phone stick to-up 1 week after the conclude of the 3rd section.

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